Package: hierBipartite Type: Package Title: Bipartite Graph-Based Hierarchical Clustering Version: 0.0.2 Authors@R: c(person("Calvin", "Chi", email = "calvin.chi@berkeley.edu", role = c("aut", "cre", "cph")), person("Woojoo", "Lee", role = c("ctb")), person("Donghwan", "Lee", role = c("ctb")), person("Youngjo", "Lee", role = c("ctb")), person("Yudi", "Pawitan", role = c("ctb"))) Maintainer: Calvin Chi Description: Bipartite graph-based hierarchical clustering performs hierarchical clustering of groups of samples based on association patterns between two sets of variables. It is developed for pharmacogenomic datasets and datasets sharing the same data structure. In the context of pharmacogenomic datasets, the samples are cell lines, and the two sets of variables are typically expression levels and drug sensitivity values. For this method, sparse canonical correlation analysis from Lee, W., Lee, D., Lee, Y. and Pawitan, Y. (2011) is first applied to extract association patterns for each group of samples. Then, a nuclear norm-based dissimilarity measure is used to construct a dissimilarity matrix between groups based on the extracted associations. Finally, hierarchical clustering is applied. License: MIT + file LICENSE Encoding: UTF-8 LazyData: true Imports: parallel, magrittr, irlba RoxygenNote: 7.1.1 Suggests: knitr, rmarkdown, testthat VignetteBuilder: knitr Repository: https://calvintchi.r-universe.dev Date/Publication: 2021-02-20 16:14:25 UTC RemoteUrl: https://github.com/calvintchi/hierbipartite RemoteRef: HEAD RemoteSha: 02d69545d0ff3998c72e4068592c1116f62eb0bb NeedsCompilation: no Packaged: 2026-10-09 11:58:48 UTC; root Author: Calvin Chi [aut, cre, cph], Woojoo Lee [ctb], Donghwan Lee [ctb], Youngjo Lee [ctb], Yudi Pawitan [ctb]